Author Correction: Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape
نویسندگان
چکیده
منابع مشابه
Bacterial membranes and lipid packing theory.
Recent physical studies on the lipids of biological membranes have emphasized the potential instability of the lamellar phase of mixtures of lipids containing unsaturated species of phosphatidylethanolamine, plasmenylethanolamine, or monoglycosyldiacylglycerols, all of which are important constituents of the membranes of different groups of prokaryotes. The polar lipid compositions of bacteria ...
متن کاملLipid-protein interactions in membranes.
The interactions of lipids with integral and peripheral proteins can be studied in reconstituted and natural membranes using spin label electron spin resonance (ESR) spectroscopy. The ESR spectra reveal a reduction in mobility of the spin-labelled lipid species, and in certain cases evidence is obtained for a partial penetration of the peripheral proteins into the membrane. The latter may be re...
متن کاملHow membranes shape protein structure.
Constitutive -helical membrane proteins (MPs) are assembled in membranes by means of a translocation/insertion process that involves the translocon complex (1). After release into the membrane’s bilayer fabric, a MP resides stably in a thermodynamic free energy minimum (evidence reviewed in Refs. 2 and 3). This means that the prediction of MP structure from the amino acid sequence is fundamenta...
متن کاملShape matters in protein mobility within membranes.
The lateral mobility of proteins within cell membranes is usually thought to be dependent on their size and modulated by local heterogeneities of the membrane. Experiments using single-particle tracking on reconstituted membranes demonstrate that protein diffusion is significantly influenced by the interplay of membrane curvature, membrane tension, and protein shape. We find that the curvature-...
متن کاملLipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes.
Cell membranes are comprised of multicomponent lipid and protein mixtures that exhibit a complex partitioning behavior. Regions of structural and compositional heterogeneity play a major role in the sorting and self-assembly of proteins, and their clustering into higher-order oligomers. Here, we use computer simulations and optical microscopy to study the sorting of transmembrane helices into t...
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2020
ISSN: 1552-4450,1552-4469
DOI: 10.1038/s41589-020-0564-3